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Research Associate (m/f)
7 dana do isteka
Poslodavac:
Kategorija:
Mjesto rada:
Sveta Nedelja
Rok prijave:
28.12.2024.
O poslu
Opis radnog mjesta:
At Genera Research Ltd., we are on a mission to revolutionize bone healing. Based in Croatia, we are a clinical-stage biotechnology company dedicated to developing recombinant human Bone Morphogenetic Protein (BMP) based products for tissue regeneration and the treatment of orthopedic, spinal, and dental conditions. Our innovative approach includes the production of recombinant human morphogenetic protein 6 (rhBMP6) and conducting clinical studies. With over 30 globally protected patents, we are proud to advance our patented innovation "OSTEOGROW" – a family of biological products designed for bone healing. Join us in our mission to make a difference in the lives of patients worldwide.
Funded by the European Regional Development Fund (State support for strategic innovation partnerships), the project aims to develop a formulation from concept (TRL 3) to a fully validated drug ready for regulatory submission (TRL 8) over three years: from January 13, 2025, to January 13, 2028. The applicant is Sartorius, with partners including Genera Research for manufacturing and clinical trials, Bekavac Dental Clinic for practical insights and protocol development, and the School of Medicine for preclinical and clinical trials.
Equal Employment Opportunity Commitment
Genera Research Ltd. provides equal employment opportunities for all individuals. Employment decisions are made without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin, or any other status protected by applicable laws. We are committed to fostering a diverse and inclusive workplace.
Project Research and development of an advanced formulation for alveolar ridge augmentation – OSTEOproDENT.
Job description
We are seeking two dedicated Research Associates to join our team in the Operations division, to work on the OSTEOproDENT project. Your primary responsibility will be hands-on laboratory work, driving innovation:
• Develop and apply aseptic techniques on cell culture; inoculation, feeding, sampling, recovery, and purification processes on a small scale (upstream and downstream process). Experience in small-scale (shaking flasks) and single-use bioreactors is considered a plus
• Contributing directly to the research and production development of rhBMP6 for our novel bone-healing drug.
• Conducting various laboratory experiments, data collection, and analysis, and supporting the overall research objectives under the supervision of senior scientists
• Advancing our scientific understanding and development efforts for new drug therapies
• Providing hands-on support in the lab and contributing to the innovative research driving our drug development projects
• Combining technical skills with analytical capabilities plays a significant part in advancing our scientific objectives
• Support process development (perfusion and intensified fed-batch) at the bench and pilot scale
Responsibilities
• Experimental Conduct: Perform laboratory experiments following GMP standards and established protocols and methodologies related to bone regeneration research
• Data Collection and Analysis: Gather, record, and analyze experimental data, ensuring accuracy and reliability of results
• Lab Maintenance: Maintain laboratory equipment and supplies, ensuring a clean and safe working environment
• Research Support: Assist senior research staff in various aspects of projects, including sample preparation, reagent preparation, and maintaining lab notes and records
• Collaborative Work: Participate in research team meetings, contributing ideas and findings to advance project goals
• Literature Reviews: Stay informed of recent scientific advances and literature in bone regeneration and related areas
• Report Writing: Assist in preparing research reports, scientific papers, and presentations
• Reporting: Reports to a Senior Scientist or Project Lead in the R&D department
Funded by the European Regional Development Fund (State support for strategic innovation partnerships), the project aims to develop a formulation from concept (TRL 3) to a fully validated drug ready for regulatory submission (TRL 8) over three years: from January 13, 2025, to January 13, 2028. The applicant is Sartorius, with partners including Genera Research for manufacturing and clinical trials, Bekavac Dental Clinic for practical insights and protocol development, and the School of Medicine for preclinical and clinical trials.
Equal Employment Opportunity Commitment
Genera Research Ltd. provides equal employment opportunities for all individuals. Employment decisions are made without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin, or any other status protected by applicable laws. We are committed to fostering a diverse and inclusive workplace.
Project Research and development of an advanced formulation for alveolar ridge augmentation – OSTEOproDENT.
Job description
We are seeking two dedicated Research Associates to join our team in the Operations division, to work on the OSTEOproDENT project. Your primary responsibility will be hands-on laboratory work, driving innovation:
• Develop and apply aseptic techniques on cell culture; inoculation, feeding, sampling, recovery, and purification processes on a small scale (upstream and downstream process). Experience in small-scale (shaking flasks) and single-use bioreactors is considered a plus
• Contributing directly to the research and production development of rhBMP6 for our novel bone-healing drug.
• Conducting various laboratory experiments, data collection, and analysis, and supporting the overall research objectives under the supervision of senior scientists
• Advancing our scientific understanding and development efforts for new drug therapies
• Providing hands-on support in the lab and contributing to the innovative research driving our drug development projects
• Combining technical skills with analytical capabilities plays a significant part in advancing our scientific objectives
• Support process development (perfusion and intensified fed-batch) at the bench and pilot scale
Responsibilities
• Experimental Conduct: Perform laboratory experiments following GMP standards and established protocols and methodologies related to bone regeneration research
• Data Collection and Analysis: Gather, record, and analyze experimental data, ensuring accuracy and reliability of results
• Lab Maintenance: Maintain laboratory equipment and supplies, ensuring a clean and safe working environment
• Research Support: Assist senior research staff in various aspects of projects, including sample preparation, reagent preparation, and maintaining lab notes and records
• Collaborative Work: Participate in research team meetings, contributing ideas and findings to advance project goals
• Literature Reviews: Stay informed of recent scientific advances and literature in bone regeneration and related areas
• Report Writing: Assist in preparing research reports, scientific papers, and presentations
• Reporting: Reports to a Senior Scientist or Project Lead in the R&D department
Vrsta posla:
stalni radni odnos, rad na određeno vrijeme
Županija:
O zaposleniku
Znanja i kvalifikacije:
Requirements
Education: Masters in biotechnology, Molecular Biology, Biochemistry, or a related scientific field.
Experience: Experience in a pharmaceutical research laboratory, or biotechnology production process, with mandatory experience in working with bioreactors or conducting pharmaceutical research. Prior experience in bone regeneration research and recombinant protein manufacturing is an advantage.
• cGMP experience within biologics, pharmaceuticals, and/or vaccine manufacturing, including expertise in aseptic techniques, suspension cell culture processes, media/feed development, recovery, purification, bulk formulation, and aseptic environments
• Experience in single-use bioreactor operations is a big advantage, including setup and process run on single-use bioreactors. Knowledge and hands-on experience in perfusion and intensified fed-batch processes are also considered as an advantage.
Skills: Strong laboratory and pilot scale skills (recombinant protein expression; aseptic techniques on cell culture; inoculation, feeding, sampling, recovery, and purification processes on a small and pilot scale (upstream and downstream process), attention to detail, analytical thinking, effective communication, and the ability to work collaboratively in a research environment.
Language: Proficiency in English, both written and spoken, at a minimum of B2 level.
The ideal candidate will have a proven track record of a deep understanding of upstream and downstream processes with mammalian cell culture and perfusion bioreactor development to produce clinical and commercial therapeutic proteins.
This role is an excellent opportunity for individuals passionate about scientific research and development. If you are eager to contribute to groundbreaking research in a dynamic laboratory, we encourage you to send your application to [email protected] or via Brza prijava link. Please note that only EU residents are eligible.
Education: Masters in biotechnology, Molecular Biology, Biochemistry, or a related scientific field.
Experience: Experience in a pharmaceutical research laboratory, or biotechnology production process, with mandatory experience in working with bioreactors or conducting pharmaceutical research. Prior experience in bone regeneration research and recombinant protein manufacturing is an advantage.
• cGMP experience within biologics, pharmaceuticals, and/or vaccine manufacturing, including expertise in aseptic techniques, suspension cell culture processes, media/feed development, recovery, purification, bulk formulation, and aseptic environments
• Experience in single-use bioreactor operations is a big advantage, including setup and process run on single-use bioreactors. Knowledge and hands-on experience in perfusion and intensified fed-batch processes are also considered as an advantage.
Skills: Strong laboratory and pilot scale skills (recombinant protein expression; aseptic techniques on cell culture; inoculation, feeding, sampling, recovery, and purification processes on a small and pilot scale (upstream and downstream process), attention to detail, analytical thinking, effective communication, and the ability to work collaboratively in a research environment.
Language: Proficiency in English, both written and spoken, at a minimum of B2 level.
The ideal candidate will have a proven track record of a deep understanding of upstream and downstream processes with mammalian cell culture and perfusion bioreactor development to produce clinical and commercial therapeutic proteins.
This role is an excellent opportunity for individuals passionate about scientific research and development. If you are eager to contribute to groundbreaking research in a dynamic laboratory, we encourage you to send your application to [email protected] or via Brza prijava link. Please note that only EU residents are eligible.
Minimalna stručna sprema:
Doktorat
Strani jezik:
engleski
Kontakt podaci poslodavca
Naziv poduzeća:
Adresa:
Svetonedeljska 2 - Kalinovica, 10436 Rakov Potok
Županija:
Zagrebačka županija
Internet adresa:
Brza prijava
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